Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 3HVG
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50226439(2-amino-6-propylpyrimidin-4(3H)-one | CHEMBL235825)
Affinity DataIC50: 2.49E+6nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50226439(2-amino-6-propylpyrimidin-4(3H)-one | CHEMBL235825)
Affinity DataKd:  4.45E+6nMAssay Description:Binding affinity to BACE1 expressed in HEK293 cells by Biocore ISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)