Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3OPM
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM123780(CHEMBL1808475 | 2-{[3-(aminomethyl)-2-(2-methylpro...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human Dipeptidyl peptidase-4 expressed in Caco-2 cells using Gly-Pro-pNA.Tos as substrate after 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM123780(CHEMBL1808475 | 2-{[3-(aminomethyl)-2-(2-methylpro...)
Affinity DataIC50: 240nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM123780(CHEMBL1808475 | 2-{[3-(aminomethyl)-2-(2-methylpro...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human DPP4 isolated from human CaCo2 cells incubated for 15 mins using Gly-Pro-pNA.Tos substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)