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Report error Found 4 Enz. Inhib. hit(s) for PDB: 3P3R

Transthyretin(Human)
The Leland Stanford Junior University

US Patent

BDBM138363(US8877795, Ro 41-0960 | US10278929, Compound Ro-41...)

Kd: 184nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair

Date in BDB:
2/21/2020
Entry Details
US Patent
PDB

Transthyretin(Human)
The Leland Stanford Junior University

US Patent

BDBM138363(US8877795, Ro 41-0960 | US10278929, Compound Ro-41...)

IC50: 755nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair

Date in BDB:
8/28/2022
Entry Details
US Patent
PDB

Transthyretin(Human)
The Leland Stanford Junior University

US Patent

BDBM138363(US8877795, Ro 41-0960 | US10278929, Compound Ro-41...)

IC50: 755nMAssay Description:The FP assay was then adapted for HTS and used to screen a 120,000 member small molecule library for compounds that displaced the FP probe from the T...More data for this Ligand-Target Pair

Date in BDB:
2/21/2020
Entry Details
US Patent
PDB

Transthyretin(Human)
The Leland Stanford Junior University

US Patent

BDBM138363(US8877795, Ro 41-0960 | US10278929, Compound Ro-41...)

IC50: 755nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair

Date in BDB:
4/13/2015
Entry Details
US Patent
PDB