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Found
1
Enz. Inhib. hit(s) for PDB:
3RDE
Target
Polyunsaturated fatty acid lipoxygenase ALOX15
(Pig)
Wayne State University
Curated by
ChEMBL
Ligand
BDBM50054838
(3-(4-Tridec-2-ynyloxymethyl-phenyl)-propionic acid...)
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Affinity Data
IC50: 35nM
Assay Description:
Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...
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Target Info
PDB
KEGG
UniProtKB/SwissProt
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Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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