Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 3UP2
TargetAurora kinase A(Human)
Moffitt Cancer Center

LigandPNGBDBM87051(Bisanilinopyrimidine, 6d | Bisanilinopyrimidine in...)
Affinity DataIC50: 28nM Kd:  40nMpH: 7.4 T: 2°CAssay Description:The formation of ADP from ATP was quantified using a coupled enzyme assay (DiscoverX) in with a fluorescent resorufin dye is generated from the inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAurora kinase A(Human)
Moffitt Cancer Center

LigandPNGBDBM87051(Bisanilinopyrimidine, 6d | Bisanilinopyrimidine in...)
Affinity DataIC50: 28nMAssay Description:In vitro enzyme activity assay using Aurora Kinase A. More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)