Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 4C1M
TargetMyeloperoxidase(Human)
University of Otago Christchurch

LigandPNGBDBM217354(2-(3,5-bistrifluoromethylbenzylamino)-6-oxo-1H-pyr...)
Affinity DataIC50: 5.01nMpH: 6.5Assay Description:Assays were performed at 22 °C with 2 nM MPO and 10 μM hydrogen peroxide (H2O2) in 20 mM NaH2PO4 buffer, pH 6.5 containing 140 mM NaCl, 10 mM ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
University of Otago Christchurch

LigandPNGBDBM217354(2-(3,5-bistrifluoromethylbenzylamino)-6-oxo-1H-pyr...)
Affinity DataKd:  15.8nMpH: 5.0Assay Description:Binding kinetics were determined by surface plasmon resonance (SPR) using a Biacore S51 (Biacore, Uppsala, Sweden). MPO (50 μg/ml dissolved in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)