Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 4CFT
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449046(CHEMBL3126215 | US9212144, 7 (Ex. 13))
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449046(CHEMBL3126215 | US9212144, 7 (Ex. 13))
Affinity DataKi:  1.12E+4nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449046(CHEMBL3126215 | US9212144, 7 (Ex. 13))
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli using L-arginine as substrate assessed as NO production by hemoglobin capture ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449046(CHEMBL3126215 | US9212144, 7 (Ex. 13))
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)