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Found
1
Enz. Inhib. hit(s) for PDB:
4HBM
Target
E3 ubiquitin-protein ligase Mdm2 [1-188]
(Human)
Amgen
US Patent
Ligand
BDBM299330
(US9593129, Example 7)
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Affinity Data
IC50: 50nM
Assay Description:
The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
PDB
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In Depth
Date in BDB:
3/12/2019
Entry Details
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US Patent
PDB
3D Structure (crystal)
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