Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4HCT
TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50399461(CHEMBL2179790)
Affinity DataIC50: 10nMAssay Description:Covalent inhibition of ITK in presence of 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50399461(CHEMBL2179790)
Affinity DataIC50: 73nMAssay Description:Covalent inhibition of ITK in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50399461(CHEMBL2179790)
Affinity DataIC50: 2.21E+3nMAssay Description:Covalent inhibition of ITK in human Jurkat cells assessed as inhibition of anti-CD3 antibody-stimulated PLCgamma phosphorylation pre-incubated before...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)