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Found
1
Enz. Inhib. hit(s) for PDB:
4HOE
Target
Dihydrofolate reductase
(Yeast)
University of Connecticut
Curated by
ChEMBL
Ligand
BDBM50329613
(5-(3-(2,5-dimethoxybiphenyl-4-yl)but-1-ynyl)-6-met...)
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Affinity Data
IC50: 36nM
Assay Description:
Inhibition of Candida albicans DHFR using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition in presence of NADPH
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
CHEMBL
PC cid
PC sid
PDB
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In Depth
Date in BDB:
2/7/2015
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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