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Found
1
Enz. Inhib. hit(s) for PDB:
4KIO
Target
Tyrosine-protein kinase ITK/TSK [357-620,Y512E]
(Human)
Glaxosmithkline
Ligand
BDBM213218
(N2-[(3S)-1-Acryloyl-3-pyrrolidinyl]-6-(4-morpholin...)
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Affinity Data
IC50: 500nM
Assay Description:
This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...
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Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
2/14/2017
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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