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Found
1
Enz. Inhib. hit(s) for PDB:
4LYN
Target
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1
(Human)
Bristol Myers Squibb
Ligand
BDBM5685
((2S)-N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]s...)
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Affinity Data
IC50: 60nM
Assay Description:
The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
8/31/2005
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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