Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 4MBS
TargetC-C chemokine receptor type 5(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50583789(CHEMBL584744)
Affinity DataIC50: 0.770nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HOS cells co-expressing Gqi-5 assessed as inhibition CCL5-stimulated Ca2+ mobilization by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 5(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50583789(CHEMBL584744)
Affinity DataEC50:  18nMAssay Description:Inhibition of CCR5-mediated HIV-1 Bal entry in human GHOST CCR5 cells assessed as decrease in viral reverse transcriptase activity by measuring [3H]t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)