Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4OD9
TargetCathepsin D(Human)
Merck Patent

US Patent
LigandPNGBDBM50055908(CHEMBL3321925 | US9884814, Compound 141)
Affinity DataIC50: 58nMpH: 5.5 T: 2°CAssay Description:In order to identify modulators of cathepsin D activity, a continuous enzymatic test was carried out with a synthetic peptide which carries a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetCathepsin D(Human)
Merck Patent

US Patent
LigandPNGBDBM50055908(CHEMBL3321925 | US9884814, Compound 141)
Affinity DataIC50: 58nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCathepsin D(Bovine)
Merck

Curated by ChEMBL
LigandPNGBDBM50055908(CHEMBL3321925 | US9884814, Compound 141)
Affinity DataIC50: 330nMAssay Description:Inhibition of cathepsin D in bovine cartilage explants assessed as reduction in sulphated GAGs level after 3 days by spectrophotometric 1,9-dimethylm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)