Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 4Y2T
TargetBifunctional epoxide hydrolase 2(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50068107(CHEMBL3402237)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of full-length human sEH (1 to 555 residues) expressed in Escherichia coli BL21 (DE3) using PHOME as substrate preincubated for 45 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50068107(CHEMBL3402237)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated with enzyme for 10 mins prior to substrate addition by fluorescence based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50068107(CHEMBL3402237)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of C-terminal His6-tagged full-length human soluble epoxide hydrolase expressed in Escherichia coli BL21(DE3) cells pre-incubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)