Compile Data Set for Download or QSAR
Report error Found 1 Enz. Inhib. hit(s) for PDB: 4YZC
TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human ERN1 using myelin basic protein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)