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Found
1
Enz. Inhib. hit(s) for PDB:
4ZZI
Target
NAD-dependent protein deacetylase sirtuin-1
(Human)
Sirtris A Gsk
Curated by
ChEMBL
Ligand
BDBM50431093
(CHEMBL2338810)
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Affinity Data
IC50: 4.30nM
Assay Description:
Inhibition of His-tagged SIRT1 (1 to 747) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate preincubated for 20 mins measured after...
More data for this Ligand-Target Pair
Target Info
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KEGG
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Ligand Info
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In Depth
Date in BDB:
9/24/2013
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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