Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5A0A
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120426(CHEMBL3617968)
Affinity DataKi:  15nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120426(CHEMBL3617968)
Affinity DataKi:  15nMAssay Description:Competitive inhibition of human neutrophil elastase using varying levels of MeOSuc-AAPV-MCA as substrate measured at 60 mins interval for up to sever...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120426(CHEMBL3617968)
Affinity DataIC50: 15nMAssay Description:Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin as substrate measured every 30 secs for 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120426(CHEMBL3617968)
Affinity DataIC50: 20nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-MCA as substrate measured at 60 mins interval for up to several hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)