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Found
1
Enz. Inhib. hit(s) for PDB:
5ANS
Target
Oxidized purine nucleoside triphosphate hydrolase
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50241029
(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
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Affinity Data
IC50: 2.06E+3nM
Assay Description:
Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
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CHEMBL
PC cid
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In Depth
Date in BDB:
3/22/2022
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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