Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 5FG4
TargetPeregrin(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataKd:  100nMAssay Description:Binding affinity to BRPF1B (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 270nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 270nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 282nMAssay Description:Alphascreen assay. Binding to BRPF1B (domain start/stop: M626-G740) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 383nMAssay Description:Alphascreen assay. Binding to BRPF1B (domain start/stop: M626-G740) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)