Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5GMP
TargetEpidermal growth factor receptor(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50131841(CHEMBL3633143)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) using Poly (Glu, Tyr)4:1 as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50131841(CHEMBL3633143)
Affinity DataIC50: 330nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50131841(CHEMBL3633143)
Affinity DataIC50: 386nMAssay Description:Inhibition of wild type EGFR phosphorylation in human A431 cells after 60 mins by mesoscale multiplex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)