Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 5I6U
LigandPNGBDBM208824(US9266878, 49a)
Affinity DataIC50: 0.300nMAssay Description:Inhibition human full length PI3Kdelta catalytic subunit/p85alpha assessed as formation of PIP3 after 30 mins by europium labeled GRP-based TR-FRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM208824(US9266878, 49a)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:PI3K isoforms were assayed under initial rate conditions in the presence of 25 mM Hepes (pH 7.4), and 2xKm ATP (100-300 uM), 10 uM PIP2, 5% glycerol,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)