Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 5IRQ
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandPNGBDBM50358201(CHEMBL1921976 | US9611270, orteronel)
Affinity DataIC50: 4nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandPNGBDBM50358201(CHEMBL1921976 | US9611270, orteronel)
Affinity DataIC50: 19nMAssay Description:Inhibition of 17,20-lyase activity of human CYP17A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandPNGBDBM50358193(CHEMBL1921977)
Affinity DataIC50: 38nMAssay Description:Inhibition of 17,20-lyase activity of human CYP17A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandPNGBDBM50358201(CHEMBL1921976 | US9611270, orteronel)
Affinity DataKd:  40nMAssay Description:Binding affinity human CYP17A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandPNGBDBM50358202(CHEMBL1921985)
Affinity DataIC50: 48nMAssay Description:Inhibition of 17,20-lyase activity of human CYP17A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandPNGBDBM50358201(CHEMBL1921976 | US9611270, orteronel)
Affinity DataIC50: 270nMAssay Description:Inhibition of human CYP17A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)