Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5LHB
TargetPoly(ADP-ribose) glycohydrolase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM371049(US10239843, Example 156)
Affinity DataEC50:  19nMAssay Description:Agonist activity at PARG (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly(ADP-ribose) glycohydrolase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM371049(US10239843, Example 156)
Affinity DataIC50: 19nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetPoly(ADP-ribose) glycohydrolase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM371049(US10239843, Example 156)
Affinity DataEC50:  19nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly(ADP-ribose) glycohydrolase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM371049(US10239843, Example 156)
Affinity DataEC50:  28nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)