Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 5NTW
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 412666BDBM412666(US10399976, Compound 2 | (S)-N-((5-(ethylsulfonyl)...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of RORgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 412666BDBM412666(US10399976, Compound 2 | (S)-N-((5-(ethylsulfonyl)...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human RORgamma by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 412666BDBM412666(US10399976, Compound 2 | (S)-N-((5-(ethylsulfonyl)...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to ROR gamma in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 412666BDBM412666(US10399976, Compound 2 | (S)-N-((5-(ethylsulfonyl)...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 412666BDBM412666(US10399976, Compound 2 | (S)-N-((5-(ethylsulfonyl)...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)