Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 5SYM
TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  280nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  280nMAssay Description:Binding affinity to human APT1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  300nMAssay Description:Inhibition of APT1 (unknown origin) by FluPol-ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-protein thioesterase 1 [L176M](Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  340nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-protein thioesterase 1 [Q83P](Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  370nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-protein thioesterase 1 [I75L,S82A](Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  1.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-protein thioesterase 1 [I75L](Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  2.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-protein thioesterase 1 [I75L,S82A,Q83P](Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)