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Found
1
Enz. Inhib. hit(s) for PDB:
5V37
Target
Histone-lysine N-methyltransferase SMYD3
(Human)
Epizyme
US Patent
Ligand
BDBM432836
(US10577363, Compound 539 | N-((1R,3R,5S)-8-(((1r,4...)
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Affinity Data
IC50: 1.30nM
Assay Description:
The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....
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Target Info
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Ligand Info
PC cid
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PDB
Similars
In Depth
Date in BDB:
11/20/2020
Entry Details
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US Patent
PDB
3D Structure (crystal)
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