Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5WA5
TargetBromodomain-containing protein 4(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM482157(LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...)
Affinity DataKd:  66nMAssay Description:Binding affinity to recombinant human N-terminal hexaHis-tagged BRD4 expressed in Escherichia coli BL21 (DE3) cells by qPCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM482157(LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...)
Affinity DataKd:  69nMAssay Description:Binding affinity to recombinant human N-terminal hexaHis-tagged BRD4 expressed in Escherichia coli BL21 (DE3) cells by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM482157(LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...)
Affinity DataKd:  194nMAssay Description:Binding affinity to recombinant human N-terminal hexaHis-tagged BRD4 expressed in Escherichia coli BL21 (DE3) cells by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)