Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) for PDB: 5X4Q
TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266780(CHEMBL4077392)
Affinity DataKd:  78nMAssay Description:Binding affinity to captured wild-type human biotinylated Avi-tagged BCL6 BTB domain (5 to 129 amino acid residues) expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266780(CHEMBL4077392)
Affinity DataKd:  78nMAssay Description:Binding affinity to human BCL6 BTP domain assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266780(CHEMBL4077392)
Affinity DataKd:  78nMAssay Description:Binding affinity to BCL6 BTB domain (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266780(CHEMBL4077392)
Affinity DataIC50: 480nMAssay Description:Inhibition of biotinylated C-terminal BCOR (unknown origin) binding to wild-type BCL6 BTB domain (5 to 129 amino acid residues) (unknown origin) by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266780(CHEMBL4077392)
Affinity DataIC50: 480nMAssay Description:Binding affinity to BCL6 BTB domain (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266780(CHEMBL4077392)
Affinity DataKd:  1.19E+3nMAssay Description:Binding affinity to recombinant human C-terminal GST-tagged BCL6 BTB domain C8Q/C67R/C84N triple mutant expressed in Escherichia coli BL21 (DE3) cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266780(CHEMBL4077392)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to human BCL6 BTP domain assessed as dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266780(CHEMBL4077392)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition FITC-labeled BCoR peptide binding to wild type human BCL6 BTB domain (5 to 129 residues) expressed in baculovirus infected Sf9 cells after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266780(CHEMBL4077392)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of VP16 activation domain-fused human BCOR (112 to 753 amino acid residues) binding to GAL4 DNA binding domain-fused wild-type human BCL6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266780(CHEMBL4077392)
Affinity DataIC50: 8.60E+3nMAssay Description:Binding affinity to BCL6 BTB domain (unknown origin) by mammalian two hybrid assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)