Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6C2I
TargetD(3) dopamine receptor(Human)
Shanghai Hansoh Biomedical Co.

US Patent
LigandPNGBDBM783876(N-(Trans-4-(2-(4-(benzo[b]thiophen-4-yl)piperazin-...)
Affinity DataIC50: 0.600nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM171819(US9085576, 320)
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE1 in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM171819(US9085576, 320)
Affinity DataIC50: 81nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)