Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 6E3E
TargetNuclear receptor ROR-gamma(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50517589(CHEMBL4100286)
Affinity DataIC50: 3.30nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50517589(CHEMBL4100286)
Affinity DataEC50:  31nMAssay Description:Agonist activity at His-tagged human RORgammaT assessed as induction of biotinylated SRC-1 peptide recruitment after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)