Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6E6E
TargetTyrosine-protein kinase Yes(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50514530(CHEMBL4548584 | US12365664, Compound 48)
Affinity DataIC50: 1nMAssay Description:All examples described herein possessed activity in a commercial assay from SelectScreen Kinase Profiling Services in ThermoFisher Scientific company...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514530(CHEMBL4548584 | US12365664, Compound 48)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human His-tagged full length SRC expressed in baculovirus expression system using tyrosine-2 peptide as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514530(CHEMBL4548584 | US12365664, Compound 48)
Affinity DataIC50: 5.5nMAssay Description:All examples described herein possessed activity in a commercial assay from SelectScreen Kinase Profiling Services in ThermoFisher Scientific company...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)