Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 6EK3
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50: 295nMAssay Description:This assay measures the substrate consumption by quantifying the remaining NAD+ through its chemical conversion to a stable fluorescent condensation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of full length recombinant His6-tagged PARP15 catalytic domain (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PARP15 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His-tagged human ARTD7 (482 to 678 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50: 1.00E+4nMAssay Description:This assay measures the substrate consumption by quantifying the remaining NAD+ through its chemical conversion to a stable fluorescent condensation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PARP15 (unknown origin) expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)