Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6F5H
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465213(CHEMBL4294359 | US10766903, Example 11)
Affinity DataIC50: 90nMAssay Description:Inhibition of USP7 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465213(CHEMBL4294359 | US10766903, Example 11)
Affinity DataIC50: 250nMAssay Description:USP7 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide ubiquitin-Lys-TAMRA substrate (U-558, Boston B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465213(CHEMBL4294359 | US10766903, Example 11)
Affinity DataEC50:  320nMAssay Description:Inhibition of USP7 in human HCT116 cells using ubiquitin-propargylamine probe as substrate incubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)