Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 6FEX
TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438155(US10618897, Example 23)
Affinity DataIC50: 25.6nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438155(US10618897, Example 23)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant GST-tagged human DDR1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438155(US10618897, Example 23)
Affinity DataIC50: 29nMAssay Description:Inhibition of GST-tagged recombinant DDR1 (unknown origin) expressed in Escherichia coli BL21 by DiscoverX KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438155(US10618897, Example 23)
Affinity DataIC50: 29nMAssay Description:Inhibition of DDR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)