Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) for PDB: 6JP5
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]nitrendipine binding to calcium channels in the rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channels of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 2.57nMAssay Description:Inhibition of L-type calcium channel in Rattus norvegicus Wistar (rat) thoracic aorta assessed as relaxation of KCl-induced vasoconstriction after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of L-type calcium channel in Rattus norvegicus Wistar (rat) thoracic aorta assessed as relaxation of KCl-induced vasoconstriction after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 28nMAssay Description:Inhibition of L-type calcium channel in Rattus norvegicus Wistar (rat) thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstrictio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 28nMAssay Description:Inhibition of L-type calcium channel in Rattus norvegicus Wistar (rat) thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstrictio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at Calcium channel in Cavia porcellus (guinea pig) ileal smooth muscle assessed as inhibition of 40 mM KCl-induced contraction co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 50nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 58nMAssay Description:Inhibition of L-type calcium channel in neonatal rat cortical neurons assessed as inhibition of veratridine-induced intracellular calcium level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 69nMAssay Description:Inhibition of Calcium channel in Cavia porcellus albino (guinea pig) ileocecal SMC assessed as inhibition of 80 mM KCl-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 260nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 300nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50101817(CHEBI:7565 | Adalat | Adalat Cc | Afeditab Cr | BA...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)