Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) for PDB: 6JPB
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2018
Entry Details
PDB3D3D Structure (crystal)
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataKi:  16nMAssay Description:Inhibitory constant against calcium channel receptors (CCRs)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataIC50: 42nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2018
Entry Details
PDB3D3D Structure (crystal)
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataIC50: 42nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptors (CCRs)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataKi:  380nMAssay Description:Displacement of [3H]diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataIC50: 450nMAssay Description:Inhibition of voltage-gated L-type Ca channel (species unknown)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Guinea pig)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataIC50: 630nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataIC50: 760nMAssay Description:Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of L-type calcium channel in Wistar rat tail artery smooth muscle cells assessed as blockade of barium-sensitive inward rectifying current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Guinea pig)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Guinea pig)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)