Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6JSZ
TargetBeta-secretase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501808(CHEMBL4465534)
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H]-JNJ-962 from BACE2 (unknown origin) expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501808(CHEMBL4465534)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of BACE2 (unknown origin) using Mca-APP Swedish Lys-Met/Asn-Leu mutant-Dnp quencher as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501808(CHEMBL4465534)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of BACE2 (unknown origin) using APP harboring Swedish Lys-Met/Asn-Leu mutant-derived peptide as substrate incubated for 2 hrs by FRET assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)