Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 6M7X
TargetCytochrome P450 11B2, mitochondrial(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM9920(CHEMBL31215 | 4-[(5S)-5H,6H,7H,8H-imidazo[1,5-a]py...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells using 11-deoxycorticosteron as substrate preincubated for 1 hr followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 11B1, mitochondrial(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM9920(CHEMBL31215 | 4-[(5S)-5H,6H,7H,8H-imidazo[1,5-a]py...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 11B2, mitochondrial(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM9920(CHEMBL31215 | 4-[(5S)-5H,6H,7H,8H-imidazo[1,5-a]py...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human aldosterone synthase expressed in V79 MZ cells pretreated with compound for 1 hr followed by addition of 500 nM 11-deoxycorticost...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 11B2, mitochondrial(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM9920(CHEMBL31215 | 4-[(5S)-5H,6H,7H,8H-imidazo[1,5-a]py...)
Affinity DataIC50: 171nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 11B1, mitochondrial(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM9920(CHEMBL31215 | 4-[(5S)-5H,6H,7H,8H-imidazo[1,5-a]py...)
Affinity DataIC50: 171nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZ cells pretreated with compound for 1 hr followed by addition of 500 nM 11-deoxycorticosterone for 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)