Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 6N33
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of California Irvine (UCI)

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 16nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of 100 uM ATP by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of California Irvine (UCI)

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 16nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of California Irvine (UCI)

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CSF1R by discoverX kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of California Irvine (UCI)

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 58nMAssay Description:Inhibition of CSF1R autophosphorylation in human THP-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of California Irvine (UCI)

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of Fms kinase activity, where inhibition of phosphorylati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of California Irvine (UCI)

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 110nMAssay Description:Inhibition of CSF1R (unknown origin) expressed in mouse EOC 20 cells assessed as inhibition of CSF1-CSF1R dependent cell proliferation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of California Irvine (UCI)

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 260nMAssay Description:Inhibition of CSF1R (unknown origin) expressed in mouse NFS-60 cells assessed as inhibition of CSF1-CSF1R dependent cell proliferation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)