Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 6N3O
TargeteIF-2-alpha kinase GCN2(Human)
Ip2Ipo Innovations

US Patent
LigandPNGBDBM615001(US20230271939, Comp Ex 1)
Affinity DataKi:  0.900nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargeteIF-2-alpha kinase GCN2(Human)
Ip2Ipo Innovations

US Patent
LigandPNGBDBM615001(US20230271939, Comp Ex 1)
Affinity DataKi:  1.90nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargeteIF-2-alpha kinase GCN2(Human)
Ip2Ipo Innovations

US Patent
LigandPNGBDBM615001(US20230271939, Comp Ex 1)
Affinity DataIC50: 5.90nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargeteIF-2-alpha kinase GCN2(Human)
Ip2Ipo Innovations

US Patent
LigandPNGBDBM615001(US20230271939, Comp Ex 1)
Affinity DataIC50: 59.2nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)