Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6NJ7
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50504041(CHEMBL4529787)
Affinity DataIC50: 13nMAssay Description:Inhibition of 11beta-HSD1 in human microsomes using [3H] cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50504041(CHEMBL4529787)
Affinity DataKi:  620nMAssay Description:Inhibition of N-terminal MKHQHQHQHQHQHQQPL-tagged 11beta-HSD1 C272S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) using cortisol a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50504041(CHEMBL4529787)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of N-terminal MKHQHQHQHQHQHQQPL-tagged 11beta-HSD1 C272S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) using cortisol a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)