Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 6OB6
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.430nM ΔG°:  -52.9kJ/mole IC50: 7.60nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human ENT1 assessed as [3H]uridine uptake by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in K562 cells after 45 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity of compound towards Nucleoside transporter es-type by facile competitive binding flow cytometric assay using the human K562 chronic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Displacement of 5-(SAENTA)-X8-fluorescein from K562 cell nucleoside transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Displacement of 5-(SAENTA)-X8-fluorescein from human ENT1 transporter in human K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.708nMAssay Description:Inhibition of human ENT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ENT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataIC50: 8.51nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)