Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 6P6K
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM432484(N-(1-((2-aminoethyl)sulfonyl)piperidin-4- yl)-5-cy...)
Affinity DataIC50: 398nMAssay Description:Inhibition of recombinant N-terminal FLAG/His-tagged SMYD3 (unknown origin) expressed in baculovirus infected insect cells using 3H-SAM as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM432484(N-(1-((2-aminoethyl)sulfonyl)piperidin-4- yl)-5-cy...)
Affinity DataIC50: 1.42E+3nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)