Affinity DataKi: 0.280nMAssay Description:Agonist activity at CB2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Binding affinity to human CB2 receptor by filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Compound was evaluated for its binding affinity against Cannabinoid receptor 2 in Guinea pig ileum (GPI) using [3H]CP-55940 ligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Binding affinity to displace [3H]CP-55940 from cloned human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity of compound was determined against to human cannabinoid receptor 2 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.390nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nM ΔG°: -54.2kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
Affinity DataEC50: 0.470nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Agonist activity at human CB2 in CHO cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nM EC50: 125nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at human CB2 receptor by GTPgamma[35S] assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cell membranes after 1 hr by beta-counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]WIN 55212-2 from human CB2 receptor incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO membranes assessed as [35S]-GTPgammaS binding after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Binding affinity to human recombinant CB2 receptor expressed in african green monkey COS cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB2 receptor expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]WIN 55212-2 from human CB2 receptor incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 expressed in CHO cells after 90 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in CHO cells membrane by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor expressed in Sf9 cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Binding affinity towards cloned human cannabinoid receptor 2More data for this Ligand-Target Pair

3D Structure (crystal)