Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) for PDB: 6SWQ
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50544300(GSK046)
Affinity DataIC50: 49nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50544300(GSK046)
Affinity DataIC50: 50nMAssay Description:Binding affinity to 6His-Thr-BRD4 (1 to 477 residues) BD2 domain Y390A mutant (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50544300(GSK046)
Affinity DataIC50: 50nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50544300(GSK046)
Affinity DataIC50: 50nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50544300(GSK046)
Affinity DataIC50: 5.01E+4nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD1/BD2 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50544300(GSK046)
Affinity DataIC50: 6.31E+4nMAssay Description:Binding affinity to 6His-Thr-BRD4 (1 to 477 residues) BD1 domain (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50544300(GSK046)
Affinity DataIC50: 6.31E+4nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD1/BD2 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50544300(GSK046)
Affinity DataIC50: 7.06E+4nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)