Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 6TOM
TargetB-cell lymphoma 6 protein(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50511632(CHEMBL4445645 | US12110286, Example 20a)
Affinity DataEC50:  54nMAssay Description:Degradation of BCL6 in human OCI-Ly1 cells incubated for 2 hrs by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50511632(CHEMBL4445645 | US12110286, Example 20a)
Affinity DataIC50: 240nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50511632(CHEMBL4445645 | US12110286, Example 20a)
Affinity DataIC50: 347nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50511632(CHEMBL4445645 | US12110286, Example 20a)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant His-tagged human BCL6 expressed in Escherichia coli BL21 AI cell incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50511632(CHEMBL4445645 | US12110286, Example 20a)
Affinity DataIC50: 520nMAssay Description:Inhibition of human BCL6 BTP domain measured by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50511632(CHEMBL4445645 | US12110286, Example 20a)
Affinity DataIC50: 523nMAssay Description:Inhibition of N-terminal thioredoxin-His6 tagged human BCL6 BTB domain (5 to 129 residues) expressed in Escherichia coli BL21-AI incubated for 2 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)