Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 6TPF
TargetTyrosine-protein kinase JAK1(Human)
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50539831(CHEMBL4639973)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 catalytic domain (850 to 1154 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK1(Human)
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50539831(CHEMBL4639973)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of JAK1 in human STAT6-bla-RA1 cells assessed as reduction in IL4-induced STAT6-signalling pre-incubated for 1 hrs before human recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)