Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6U6F
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKi:  94nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKi:  94nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from His-tagged human MCL-1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKd:  670nMAssay Description:Binding affinity to immobilized biotin-labeled and N-terminal His6-tagged human Mcl-1 expressed in Escherichia coli Rosetta2 DE3 by biolayer interfer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)