Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 6V52
TargetIndoleamine 2,3-dioxygenase 1(Human)
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50538500(CHEMBL4636709)
Affinity DataIC50: 9nMAssay Description:Inhibition of IDO1 in IFN gamma-stimulated human HeLa cells measured after 48 hrs by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50538500(CHEMBL4636709)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of heme binding to IDO1 in interferon-gamma-induced human HeLa cells assessed as reduction in N-formylkynurenine production using L-trypto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50538500(CHEMBL4636709)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Pharmaron Beijing

Curated by ChEMBL
LigandPNGBDBM50538500(CHEMBL4636709)
Affinity DataIC50: 22nMAssay Description:Inhibition of IDO1 in IFNgamma/LPS stimulated human whole blood assessed as unbound concentration using kynurenine/tryptophan as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)